ChemicalBook CAS DataBase List 2-Chlorothioxanthone

2-Chlorothioxanthone synthesis

12synthesis methods

Product Name:2-Chlorothioxanthone
CAS Number:86-39-5
Molecular formula:C13H7ClOS
Molecular Weight:246.71

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86-39-5
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Yield:86-39-5 96%

Reaction Conditions:

with potassium hexafluorophosphate;iron(III) nitrate monohydrate;oxygen in acetonitrile at 80; for 12 h;Reagent/catalyst;Temperature;Concentration;

Steps:

22 Example 22:2-chlorothioxanthone (formula (2-10))

To a 35 mL tube, 1 mmol was added2-chlorothianthracene (formula (1-10)),0.1 mmol of Fe (NO3) 3 · 9H2O, 0.2 mmol of KPF6 and3mL of acetonitrile, oxygen to replace the tube air, sealed with a rubber stopper bottle,Insert the oxygen balloon, the reaction bottle into the preheated oil bath heated to 80 , the reaction 2h. Filtration, the filtrate vacuum distillation solvent, and then column chromatography separation,A mixture of ethyl acetate / petroleum ether in a volume ratio of 1:50 was used as the eluent,The eluate containing the target compound was collected and the solvent was evaporated to give the product2-chlorothioxanthone, the isolated yield was 96%.

References:

CN106905284,2017,A Location in patent:Paragraph 0039