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ChemicalBook CAS DataBase List 2-Hydroxy-5-trifluoromethylbenzonitrile
142167-36-0

2-Hydroxy-5-trifluoromethylbenzonitrile synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: bromine / CH2Cl2 / 38 h / Ambient temperature
2: dimethylformamide / 2 h / Heating

References:

Yamamoto, Satoshi;Hashiguchi, Shohei;Miki, Shokyo;Igata, Yumiko;Watanabe, Toshifumi;Shiraishi, Mitsuru [Chemical and Pharmaceutical Bulletin,1996,vol. 44,# 4,p. 734 - 745]