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65109-82-2

2'-methoxybiphenyl-4-ol synthesis

11synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: magnesium / tetrahydrofuran
1.2: 0 - 20 °C
2.1: toluene-4-sulfonic acid / benzene / 4 h / Reflux
3.1: iodine / 2 h / 20 °C / Inert atmosphere

References:

Subba Reddy;Nageshwar Rao;Siva Senkar Reddy;Somaiah;Yadav;Subramanyam, Ravi [Tetrahedron Letters,2014,vol. 55,# 5,p. 1049 - 1051]