(2-METHYLPHENOXY)ACETIC ACID synthesis
- Product Name:(2-METHYLPHENOXY)ACETIC ACID
- CAS Number:1878-49-5
- Molecular formula:C9H10O3
- Molecular Weight:166.17
93917-68-1
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$58.50/5g
1878-49-5
155 suppliers
$15.00/1g
Yield:1878-49-5 81%
Reaction Conditions:
with sodium hydroxide in ethanol;waterReflux;
Steps:
4 4.1.2.1 General synthetic procedure for phenoxyacetic acid analogues (4a-j)
General procedure: Compounds (3a-j,0.02mol) were dissolved in ethanol (15mL), sodium hydroxide (0.035mol) in water (5mL) was added, and the mixture was refluxed for 5-9h. The reaction mixture was cooled and acidified with 2N hydrochloric acid. The precipitate was filtered, washed with water, and finally recrystallized from methanol to afford desired compounds (4a-j). Compound (4a) is takenas a representative example to explain physical and characterization data.
References:
Mohammed, Yasser Hussein Eissa;Malojirao, Vikas H.;Thirusangu, Prabhu;Al-Ghorbani, Mohammed;Prabhakar;Khanum, Shaukath Ara [European Journal of Medicinal Chemistry,2018,vol. 143,p. 1826 - 1839]
94-74-6
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$12.00/1 G
1878-49-5
155 suppliers
$15.00/1g
3926-62-3
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$16.69/250g
95-48-7
459 suppliers
$17.00/25g
1878-49-5
155 suppliers
$15.00/1g