2-(NAPHTHALEN-1-YLAMINO)-BENZOIC ACID synthesis
- Product Name:2-(NAPHTHALEN-1-YLAMINO)-BENZOIC ACID
- CAS Number:13278-41-6
- Molecular formula:C17H13NO2
- Molecular Weight:263.29
Yield:13278-41-6 94%
Reaction Conditions:
with copper(I) oxide;copper;potassium carbonate in 2-ethoxy-ethanol at 130;
Steps:
1.1 (1) Sub-1 I-1 Synthesis
The starting material, 2-bromobenzoic acid (41.69 g, 207.4 mmol) to a round bottom flask was charged with 2-ethoxyethanol in dissolved after, naphthalen-1-amine (31.18 g, 217.8 mmol), Cu (1.19 g, 18.7 mmol), Cu2O ( 1.19 g, 8.3 mmol), was added K2CO3 (28.66g, 207.4 mmol) and the resulting mixture was stirred at 130 ° C. Once the reaction is complete, the lower the temperature of the reaction charcoal (charcoal)And it filtered through Celite (Celite) with water. The filtrate was put in a hydrochloric acid (diluted HCl) to form a precipitate. Filtering and drying the resulting precipitate was again with 5% Na2CO3 Celite (Celite) dissolved product with an aqueous solution to 51.33 g (yield: 94%) of the
References:
KR2015/64442,2015,A Location in patent:Paragraph 0109; 0110-0111
