2-Pyrrolidinemethanol, α-phenyl-, (αR,2S)- synthesis

13synthesis methods

147-85-3 Synthesis

Yield:-

Steps:

Multi-step reaction with 4 steps
1: NaOH
2: 1.) Ph₂POCl
3: diisobutylaluminum hydride
4: KOH / methanol

References:

Soai, Kenso;Ookawa, Atsuhiro;Kaba, Tatsuya;Ogawa, Kazuo [Journal of the American Chemical Society,1987,vol. 109,# 23,p. 7111 - 7115]

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