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222167-42-2

2-((TriMethylsilyl)ethynyl)nicotinaldehyde synthesis

2synthesis methods
-

Yield:222167-42-2 91%

Reaction Conditions:

with 1,4-diaza-bicyclo[2.2.2]octane;bis-triphenylphosphine-palladium(II) chloride;copper(l) iodide in tetrahydrofuran at 20; for 1 h;Sonogashira Cross-Coupling;

References:

Beghennou, Anissa;Passador, Kevin;Passador, Anthony;Corcé, Vincent;Thorimbert, Serge;Botuha, Candice [European Journal of Organic Chemistry,2020,vol. 2020,# 36,p. 5880 - 5889]