(2S, 4S)-BOC-4-AMINO-1-FMOC-PYRROLIDINE-2-CARBOXYLIC ACID synthesis
- Product Name:(2S, 4S)-BOC-4-AMINO-1-FMOC-PYRROLIDINE-2-CARBOXYLIC ACID
- CAS Number:221352-74-5
- Molecular formula:C25H28N2O6
- Molecular Weight:452.5
89813-47-8
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221352-74-5
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Yield:-
Steps:
Multi-step reaction with 6 steps
1: pyridine / 0 - 20 °C
2: sodium azide / N,N-dimethyl-formamide / 65 °C
3: trifluoroacetic acid / dichloromethane / 2 h
4: sodium hydrogencarbonate / 1,4-dioxane / 20 °C
5: palladium on activated charcoal; hydrogen / 72 h / 20 °C / 6080.41 Torr
6: triethylamine / 1,4-dioxane; water / 0 - 20 °C
References:
Shi, Saijian;Xu, Jian;Feng, LingLing;Fan, Xin;Chen, Zhen;Qin, Yajuan;Chung, Nga N.;Li, Tingyou;Schiller, Peter W. [Chemical Biology and Drug Design,2020,vol. 96,# 5,p. 1305 - 1314]
![1,2-Pyrrolidinedicarboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1,2-bis(phenylmethyl) ester, (2S,4S)-](/CAS/20210305/GIF/853063-23-7.gif)
853063-23-7
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221352-74-5
72 suppliers
$37.00/100mg
329191-57-3
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221352-74-5
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168263-82-9
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28920-43-6
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221352-74-5
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$37.00/100mg