3-CHLORO-4-(CYCLOPROPYLMETHOXY)BENZALDEHYDE synthesis
1synthesis methods
- Product Name:3-CHLORO-4-(CYCLOPROPYLMETHOXY)BENZALDEHYDE
- CAS Number:883519-07-1
- Molecular formula:C11H11ClO2
- Molecular Weight:210.66
Yield:883519-07-1 97%
Steps:
3-Chloro-4-hydroxybenzaldehyde was reacted with bromomethylcyclopropane in 97% yield to furnish 3-chloro-4-cyclopropylmethoxybenzaldehyde. 1H-NMR (400 MHz, CDCl3 ) δ (ppm): 9.845 (s, IH), 7.909 (s, IH), 7.749-7.728 (d, IH, J=8.4Hz), 7.011-6.990 (d, IH, J=8.4Hz), 4.001-3.985 (d, 2H, J=6.4Hz), 1.345 (m, IH), 0.705-0.686 (d, 2H, J=7.6Hz), 0.434-0.424 (d, 2H, J=4Hz).
References:
WO2010/127212,2010,A1 Location in patent:Page/Page column 36