ChemicalBook CAS DataBase List 3-oxopropanoic acid

3-oxopropanoic acid synthesis

13synthesis methods

Product Name:3-oxopropanoic acid
CAS Number:926-61-4
Molecular formula:C3H4O3
Molecular Weight:88.06

127-17-3 Synthesis

127-17-3
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107-95-9
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56-41-7 Synthesis

56-41-7
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926-61-4
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Yield:-

Reaction Conditions:

with pyridoxal 5'-phosphate;recombinant ω-transaminase from Burkholderia vietnamiensis G4 in aq. phosphate buffer; pH=7.4 at 37; for 0.0833333 h;Enzymatic reaction;enantioselective reaction;

Steps:

2.7. Substrate specificity and enantioselectivity
General procedure: Amino donor specificity was assayed by following the similar procedure of Section 2.5. The amino donor substrates (10 mM) listed in Table 1 reacted with pyruvate (10 mM) as amino acceptor. For racemic amino donor, the concentration was 20 mM. After the reaction, residual pyruvate was analyzed by HPLC according to Section 2.10. Amino acceptor specificity was assayed by following the similar procedure of Section 2.5. The amino acceptor substrates (10 mM) listed in Table 2 reacted with (S)-α-MBA (10 mM) as amino donor. After the reaction, the amount of produced acetophenone was analyzed and the ee values of the produced amines were determined according to Section 2.10.

References:

Jiang, Jinju;Chen, Xi;Feng, Jinhui;Wu, Qiaqing;Zhu, Dunming [Journal of Molecular Catalysis B: Enzymatic,2014,vol. 100,p. 32 - 39]

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617-45-8 Synthesis