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ChemicalBook CAS DataBase List (3-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL
131747-44-9

(3-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL synthesis

3synthesis methods
65753-47-1 Synthesis
2-Chloro-3-(trifluoromethyl)pyridine

65753-47-1
379 suppliers
$8.00/5g

-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 2) m-chloroperbenzoic acid / 1) Pd(PPh3)4 / 1) dioxane, hexane, reflux, 2) CHCl3, rt
2: 54 percent / Heating
3: 76 percent / aq. NaOH / methanol / 1.5 h / Ambient temperature

References:

Ashimori;Ono;Uchida;Ohtaki;Fukaya;Watanabe;Yokoyama [Chemical and Pharmaceutical Bulletin,1990,vol. 38,# 9,p. 2446 - 2458]

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