2-(2,3-Dioxo-2,3-dihydro-1H-indol-1-yl)-N-(4-methylphenyl)acetamide synthesis

3synthesis methods

Product Name:2-(2,3-Dioxo-2,3-dihydro-1H-indol-1-yl)-N-(4-methylphenyl)acetamide
CAS Number:301819-41-0
Molecular formula:C17H14N2O3
Molecular Weight:294.3

91-56-5 Synthesis

91-56-5
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16634-82-5
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2-(2,3-Dioxo-2,3-dihydro-1H-indol-1-yl)-N-(4-methylphenyl)acetamide

301819-41-0
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Yield:301819-41-0 60%

Reaction Conditions:

Stage #1: indole-2,3-dionewith sodium hydride in N,N-dimethyl-formamide at 0; for 0.25 h;
Stage #2: N-(p-tolyl)-2-chloroacetamide in N,N-dimethyl-formamide; for 1 h;

References:

Firoozpour, Loghman;Gao, Lixin;Moghimi, Setareh;Pasalar, Parvin;Davoodi, Jamshid;Wang, Ming-Wei;Rezaei, Zahra;Dadgar, Armin;Yahyavi, Hoda;Amanlou, Massoud;Foroumadi, Alireza [Journal of Enzyme Inhibition and Medicinal Chemistry,2020,vol. 35,# 1,p. 1674 - 1684]

106-49-0
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301819-41-0
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References

62-53-3 Synthesis

62-53-3
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301819-41-0
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