Dithiocarbonic acid O-tert-butyl ester S-methyl ester synthesis
- Product Name:Dithiocarbonic acid O-tert-butyl ester S-methyl ester
- CAS Number:37527-08-5
- Molecular formula:C6H12OS2
- Molecular Weight:164.29
75-15-0
267 suppliers
$40.00/100g
865-47-4
713 suppliers
$14.00/25g
74-88-4
357 suppliers
$15.00/10g
37527-08-5
1 suppliers
inquiry
Yield:37527-08-5 60%
Reaction Conditions:
Stage #1: carbon disulfide;potassium-t-butoxide in 5,5-dimethyl-1,3-cyclohexadiene at 80; for 1 h;
Stage #2: methyl iodine in 5,5-dimethyl-1,3-cyclohexadiene;diethyl ether at 20; for 20 h;
Steps:
Methyl O-(tert-butyl)S-dithiocarbonate
Potassium tert-butoxide (73.7g, 0.66mol) was added to xylene (2L), the temperature was raised to 80°C, carbon disulfide (50g, 0.66mol) was added dropwise, the reaction was carried out at 80°C for 1 h, cooled to room temperature, filtered, and ether Washed and dried to obtain 100 g of light yellow solid. The solid was added to ether (1 L), methyl iodide (113 g, 0.796 mol) was added, the reaction was carried out at room temperature for 20 h, filtered, the solid was washed with ether, and the filtrate was concentrated under reduced pressure to obtain the title compound INT- 3B (65g, 60%).
References:
WO2022/135390,2022,A1 Location in patent:Page/Page column 40
75-15-0
267 suppliers
$40.00/100g
75-65-0
783 suppliers
$10.00/10ml
74-88-4
357 suppliers
$15.00/10g
37527-08-5
1 suppliers
inquiry