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ChemicalBook CAS DataBase List 4-(1H-1,2,4-TRIAZOL-1-YL)BENZALDEHYDE

4-(1H-1,2,4-TRIAZOL-1-YL)BENZALDEHYDE synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 48 percent / NaH / dimethylsulfoxide / 18 h / 100 °C
2: 77 percent / NaBH4, CaCl2 / tetrahydrofuran / Ambient temperature
3: 49 percent / pyridinium chlorochromate (PCC) / CH2Cl2 / 1.5 h / Ambient temperature

References:

Artico;Silvestri;Stefancich;Avigliano;Di Giulio;Maccarrone;Agostinelli;Mondovi;Morpurgo [European Journal of Medicinal Chemistry,1992,vol. 27,# 3,p. 219 - 228]

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