4-(1H-IMIDAZOL-1-YL)BENZOIC ACID synthesis
- Product Name:4-(1H-IMIDAZOL-1-YL)BENZOIC ACID
- CAS Number:17616-04-5
- Molecular formula:C10H8N2O2
- Molecular Weight:188.18
288-32-4
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$5.00/25g
619-58-9
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$8.00/5g
17616-04-5
131 suppliers
$20.00/250mg
Yield:17616-04-5 93 %Chromat.
Reaction Conditions:
with C16H12ClN3OPdS;potassium hydroxide in dimethyl sulfoxide at 110; for 10 h;
Steps:
2.3. Catalytic arylation of nitrogen-containing heterocycles with aryl halides
General procedure: Arylhalide (1.0 mM), nitrogen-containing heterocycle (1.2 mM), KOH (2 mM), and the catalyst (0.75 M%) were stirred in dimethyl sulfoxide (DMSO) (4 mL) at 110 °C for 10 h. After completion of the reaction, the mixture was cooled to room temperature, diluted with ethyl acetate (10 mL) and filtered. The filtrate was concentrated and the residue was purified by column chromatography on silica gel using hexane/ethyl acetate(70 : 30) as eluent to afford the desired product. The products have been characterized by 1H NMR spectroscopy.
References:
Anitha, Panneerselvam;Manikandan, Rajendran;Viswanathamurthi, Periasamy [Journal of Coordination Chemistry,2015,vol. 68,# 19,p. 3537 - 3550]
101184-08-1
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$15.00/250mg
17616-04-5
131 suppliers
$20.00/250mg
288-32-4
1051 suppliers
$5.00/25g
586-76-5
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$10.00/1g
17616-04-5
131 suppliers
$20.00/250mg
10040-98-9
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$6.00/1g
17616-04-5
131 suppliers
$20.00/250mg
288-32-4
1051 suppliers
$5.00/25g
74-11-3
603 suppliers
$5.00/1g
17616-04-5
131 suppliers
$20.00/250mg