4-(2-BROMOETHOXY)PHENOL synthesis
- Product Name:4-(2-BROMOETHOXY)PHENOL
- CAS Number:31406-95-8
- Molecular formula:C8H9BrO2
- Molecular Weight:217.06
3351-59-5
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$93.00/1g
31406-95-8
32 suppliers
$101.00/5g
Yield:31406-95-8 99%
Reaction Conditions:
with hydrogen;palladium 10% on activated carbon in tetrahydrofuran;ethanol; under 2068.65 Torr;
Steps:
3
2-(4-Benzyloxy-phenoxy)-ethyl bromide (EXAMPLE 1; 70 g, 227 mmol) was dissolved in THF (500 mL). To this solution was added Pd on carbon (10 wt %, 7 g) as a suspension in ethanol (50 mL). The resulting suspension was placed on a Parr hydrogenator at 40 psi of H2 and shaken overnight. The reaction mixture was filtered through a pad of diatomaceous earth, and the filtrate was concentrated under reduced pressure to give 48.5 g (224 mmol, 99% yield) of a tan solid. 1H NMR (400 MHz, CDCl3): 6.83 (d, J=9.1, 2H), 6.77 (d, J=9.1, 2H), 4.51 (s, 1H), 4.24 (t, J=6.3, 2H), 3.62 (t, J=6.3, 2H).
References:
US2008/194630,2008,A1 Location in patent:Page/Page column 28
106-93-4
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123-31-9
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31406-95-8
32 suppliers
$101.00/5g
589-10-6
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$18.00/5g
31406-95-8
32 suppliers
$101.00/5g