4-{[3-(trifluoromethyl)benzyl]oxy}benzoic acid synthesis
- Product Name:4-{[3-(trifluoromethyl)benzyl]oxy}benzoic acid
- CAS Number:632366-16-6
- Molecular formula:C15H11F3O3
- Molecular Weight:296.24
![Benzoic acid, 4-[[3-(trifluoromethyl)phenyl]methoxy]-, methyl ester](/CAS/20210305/GIF/632366-15-5.gif)
632366-15-5
1 suppliers
inquiry
632366-16-6
9 suppliers
$126.00/500mg
Yield:632366-16-6 81%
Reaction Conditions:
Stage #1: 4-(3-trifluoromethyl-benzyloxy)-benzoic acid methyl esterwith water;sodium hydroxide in methanol at 75; for 2 h;
Stage #2: with hydrogenchloride in water; pH=5;
References:
Sun, Chiyu;Li, Yangsheng;Shi, Ailong;Zhang, Jingzhou;Li, Yafei;Zhao, Mingming;Zhang, Lijuan;Zheng, Huachuan;Meng, Ying;Ding, Huaiwei;Song, Hongrui [MedChemComm,2015,vol. 6,# 6,p. 1137 - 1142] Location in patent:supporting information
99-76-3
813 suppliers
$5.00/25g
632366-16-6
9 suppliers
$126.00/500mg
402-23-3
260 suppliers
$6.00/1g
632366-16-6
9 suppliers
$126.00/500mg