4-Amino-2-chlorobenzoic acid synthesis
- Product Name:4-Amino-2-chlorobenzoic acid
- CAS Number:2457-76-3
- Molecular formula:C7H6ClNO2
- Molecular Weight:171.58
99-60-5
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2457-76-3
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Yield:2457-76-3 88%
Reaction Conditions:
with isopropyl alcohol;potassium hydroxide at 20; for 2.5 h;Catalytic behavior;
Steps:
General procedure for the reduction in nitroarenes
First, NaBH4 (1 mmol) was used as a reducing agent forthe conversion of Ag (+ 1) to Ag (0) in methanol at roomtemperature for 2 h. After that, the Ag/MMT was filtered andused as a catalyst. Then, in a typical procedure, a mixtureof 4-nitrophenol (0.1 mmol), KOH (0.15 mmol), isopropylalcohol (3 mL), and Ag/MMT catalyst (50 mg) 1.01 wt%was stirred at room temperature for an appropriate time(Scheme 2). After the completion of the reaction (monitoredby GC), the catalyst was separated by filtration. The ensuingproduct was extracted with ethyl acetate and repeatedlywashed with water (3-4 times) to remove KOH. The resultingsolvent was evaporated to dryness in vacuum.
References:
Karami, Kazem;Rahimi, Mahzad;Dinari, Mohammad [Journal of the Iranian Chemical Society,2018,vol. 15,# 2,p. 281 - 291]
121-86-8
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2457-76-3
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38667-55-9
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$45.00/50mg
2457-76-3
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588-07-8
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2457-76-3
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5568-33-2
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2457-76-3
299 suppliers
$5.00/1g