4-BIPHENYLSULFONYL CHLORIDE synthesis
- Product Name:4-BIPHENYLSULFONYL CHLORIDE
- CAS Number:1623-93-4
- Molecular formula:C12H9ClO2S
- Molecular Weight:252.72
92-52-4
380 suppliers
$9.00/5g
1623-93-4
167 suppliers
$5.00/5mg
Yield:-
Reaction Conditions:
with chlorosulfonic acid in chloroform at 20; for 0.75 h;
Steps:
Syntheses of substituted benzenesulfonyl chlorides
General procedure: The chemical synthesis was started with chlorosulfonylationof the substituted benzenes (S1) individually in dry chloroformby dropwise addition of chlorosulfonic acid over a period of45-60 mins at 0-5 C. After completion of chlorosulfonic acid addition,the reaction mixture was stirred for additional 45 min atroom temperature and the mixture was poured over crushed ice.The mixture was extracted thrice with 50 ml chloroform whichwas dried overnight in presence of anhydrous sodium sulfate. Afterevaporation of the solvent chloroform, substituted benzenesulfonylchlorides (I1) were obtained individually in solid formswhich were used for next step without any purification.
References:
Adhikari, Nilanjan;Halder, Amit K.;Mallick, Sumana;Saha, Achintya;Saha, Kishna D.;Jha, Tarun [Bioorganic and Medicinal Chemistry,2016,vol. 24,# 18,p. 4291 - 4309]
2113-68-0
78 suppliers
$64.09/10g
1623-93-4
167 suppliers
$5.00/5mg
92-67-1
231 suppliers
$15.90/1g
1623-93-4
167 suppliers
$5.00/5mg
92-66-0
541 suppliers
$10.00/1g
1623-93-4
167 suppliers
$5.00/5mg