4-Iodo-5-Methoxy-2-nitro-phenylaMine synthesis
- Product Name:4-Iodo-5-Methoxy-2-nitro-phenylaMine
- CAS Number:335349-66-1
- Molecular formula:C7H7IN2O3
- Molecular Weight:294.05
67-56-1
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$9.00/25ml
335349-57-0
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$16.00/250mg
335349-66-1
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$250.00/1g
Yield:335349-66-1 97%
Reaction Conditions:
with potassium hydroxide in dimethyl sulfoxide at 30 - 60; for 4 h;Large scale;
Steps:
(2) Preparation of compound 3
Compound 2S 2-nitro-4-iodo-5-chloroaniline (2200 g, 7.4 mol) was added to a solution of 7.3 L of dimethylsulfoxide (DMS0) and7.3 L methanol (Μ0H) mixed solution, then add K0H (1040g, 18.4mo 1),Temperature control at 30 ° C plus finish. And then heated to 60 ° C reaction 4h, TLC detection reaction is complete, then cooled to room temperature, the reaction solution into 10L of water, Stirred for 15min, filtered, the filter cake washed with water to neutral, drying the compound 3S 3-methoxy-4-iodo-5-nitro-aniline(2100 g, 7.14 mol) Yield 97%
References:
CN106496037,2017,A Location in patent:Paragraph 0029-0032
335349-57-0
62 suppliers
$16.00/250mg
335349-66-1
9 suppliers
$250.00/1g
1635-61-6
305 suppliers
$13.00/25g
335349-66-1
9 suppliers
$250.00/1g