4-PROPYLOXYBENZYLAMINE synthesis
- Product Name:4-PROPYLOXYBENZYLAMINE
- CAS Number:21244-33-7
- Molecular formula:C10H15NO
- Molecular Weight:165.23
60758-84-1
61 suppliers
$15.00/500mg
21244-33-7
31 suppliers
$126.00/500mg
Yield:21244-33-7 85%
Reaction Conditions:
with lithium aluminium tetrahydride in tetrahydrofuran; for 3 h;Reflux;
Steps:
140 1 -(4-propoxyphenyl)methanamine
4-propoxybenzonitrile (8.00 g, 49.6 mmol) was dissolved in tetrahydrofuran (50 ml). Lithium aluminiumhydride (2.82 g, 74.4 mmol) was added and the suspension was refluxed for 3h. After cooling, the reaction mixture was quenched with water (3 ml), aqueous sodium hydroxide solution (15%, 3 ml) and water (9 ml). The precipitate was filtered, the filtrate dried (sodium sulfate) and evaporated to give the desired intermediate (7.00 g, 85%).
References:
WO2019/40107,2019,A1 Location in patent:Paragraph 00677-00678
767-00-0
582 suppliers
$6.00/25g
21244-33-7
31 suppliers
$126.00/500mg
40141-11-5
7 suppliers
$134.31/250mgs:
21244-33-7
31 suppliers
$126.00/500mg