4-PROPOXYBENZONITRILE synthesis
- Product Name:4-PROPOXYBENZONITRILE
- CAS Number:60758-84-1
- Molecular formula:C10H11NO
- Molecular Weight:161.2
767-00-0
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107-08-4
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60758-84-1
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Yield:60758-84-1 98%
Reaction Conditions:
with potassium carbonate in N,N-dimethyl-formamide at 70; for 12 h;
Steps:
140 4-propoxybenzonitrile
4-hydroxybenzonitrile (6.00 g, 50.4 mmol), potassium carbonate (17.4 g, 126 mmol) and n-propyl iodide (21.4 g, 126 mmol) were heated in DMF (70 ml) at 70 °C for 12h. After cooling, water (150 ml) was added and the reaction mixture was extracted with diethyl ether (2 x 250ml). The combined organic phase was washed with water (200 ml), dried (sodium sulfate) and evaporated to give the desired intermediate (8.00 g, 98%).
References:
WO2019/40107,2019,A1 Location in patent:Paragraph 00675-00676
71-23-8
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767-00-0
573 suppliers
$6.00/25g
60758-84-1
59 suppliers
$15.00/500mg
623-03-0
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$6.00/25g
71-23-8
791 suppliers
$12.00/100g
60758-84-1
59 suppliers
$15.00/500mg
767-00-0
573 suppliers
$6.00/25g
106-94-5
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$10.00/5ml
60758-84-1
59 suppliers
$15.00/500mg
80122-67-4
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60758-84-1
59 suppliers
$15.00/500mg