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ChemicalBook CAS DataBase List METHYL 3-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)THIOPHENE-2-CARBOXYLATE

METHYL 3-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)THIOPHENE-2-CARBOXYLATE synthesis

1synthesis methods
22288-78-4 Synthesis
Methyl 3-amino-2-thiophenecarboxylate

22288-78-4
386 suppliers
$11.00/5g

METHYL 3-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)THIOPHENE-2-CARBOXYLATE

465514-23-2
18 suppliers
inquiry

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Yield:-

Reaction Conditions:

Stage #1: maleic anhydride;Methyl 3-aminothiophene-2-carboxylate in diethyl ether at 20;
Stage #2: with sodium acetate;acetic anhydride at 120;

References:

Chen, Hai-Jun;Liu, Yong;Wang, Li-Na;Shen, Qiang;Li, Jia;Nan, Fa-Jun [Bioorganic and Medicinal Chemistry Letters,2010,vol. 20,# 9,p. 2876 - 2879] Location in patent:scheme or table