METHYL 3-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)THIOPHENE-2-CARBOXYLATE synthesis
- Product Name:METHYL 3-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)THIOPHENE-2-CARBOXYLATE
- CAS Number:465514-23-2
- Molecular formula:C10H7NO4S
- Molecular Weight:237.23
108-31-6
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Yield:-
Reaction Conditions:
Stage #1: maleic anhydride;Methyl 3-aminothiophene-2-carboxylate in diethyl ether at 20;
Stage #2: with sodium acetate;acetic anhydride at 120;
References:
Chen, Hai-Jun;Liu, Yong;Wang, Li-Na;Shen, Qiang;Li, Jia;Nan, Fa-Jun [Bioorganic and Medicinal Chemistry Letters,2010,vol. 20,# 9,p. 2876 - 2879] Location in patent:scheme or table