DIETHYL (1-TRITYL-1H-IMIDAZOL-4-YL)METHYLPHOSPHONATE synthesis
- Product Name:DIETHYL (1-TRITYL-1H-IMIDAZOL-4-YL)METHYLPHOSPHONATE
- CAS Number:473659-21-1
- Molecular formula:C27H29N2O3P
- Molecular Weight:460.5
103057-10-9
46 suppliers
$45.00/50mg
762-04-9
342 suppliers
$10.00/10g
473659-21-1
19 suppliers
$492.00/500mg
Yield:473659-21-1 86%
Reaction Conditions:
Stage #1: phosphonic acid diethyl esterwith lithium hexamethyldisilazane in tetrahydrofuran at -70;
Stage #2: 4-chloromethyl-1-tritylimidazole in tetrahydrofuran at -70 - 25;Michaelis-Becker reaction;
References:
Harusawa, Shinya;Koyabu, Shuji;Inoue, Yasutoshi;Sakamoto, Yasuhiko;Araki, Lisa;Kurihara, Takushi [Synthesis,2002,# 8,p. 1072 - 1078]
103057-10-9
46 suppliers
$45.00/50mg
473659-21-1
19 suppliers
$492.00/500mg
103057-10-9
46 suppliers
$45.00/50mg
122-52-1
257 suppliers
$9.00/5g
473659-21-1
19 suppliers
$492.00/500mg
76-83-5
720 suppliers
$6.00/25g
473659-21-1
19 suppliers
$492.00/500mg
33769-07-2
98 suppliers
$110.00/500mg
473659-21-1
19 suppliers
$492.00/500mg