5(10)-Estrene-3β,17α-diol synthesis
- Product Name:5(10)-Estrene-3β,17α-diol
- CAS Number:268734-48-1
- Molecular formula:C18H28O2
- Molecular Weight:276.42
Yield:-
Steps:
Multi-step reaction with 6 steps
1: sodium carbonate / methanol / 16 h / Reflux; Inert atmosphere
2: sodium tetrahydroborate / ethanol; water / 72 h / 20 °C / Inert atmosphere
3: di-isopropyl azodicarboxylate; 2-(diphenylphosphino)pyridine / toluene / 24 h / 80 °C / Cooling with ice; Inert atmosphere
4: lithium; ammonia / ethanol; 1,4-dioxane; diethyl ether / 0.33 h / Inert atmosphere
5: oxalic acid / methanol; water / 2 h / 20 °C / Inert atmosphere
6: potassium hydroxide; chloro{[(1S,2S)-(+)-2-amino-1,2-diphenylethyl](4-toluenesulfonyl)amido}(p-cymene)ruthenium(II) / isopropyl alcohol / 20 h / 20 °C / Inert atmosphere
References:
Balssa, Frédéric;Fischer, Michael;Bonnaire, Yves [Steroids,2014,vol. 86,p. 1 - 4]
1035-77-4
42 suppliers
$697.34/100MG
268734-49-2
3 suppliers
inquiry
268734-48-1
5 suppliers
inquiry
