5-broMo-2-(1,3-oxazol-5-yl)pyridine synthesis
- Product Name:5-broMo-2-(1,3-oxazol-5-yl)pyridine
- CAS Number:380380-74-5
- Molecular formula:C8H5BrN2O
- Molecular Weight:225.04
31181-90-5
330 suppliers
$5.00/250mg
36635-61-7
498 suppliers
$5.00/5g
380380-74-5
13 suppliers
$124.00/500mg
Yield:380380-74-5 90%
Reaction Conditions:
with potassium carbonate in methanol; for 5 h;Reflux;
Steps:
1.62
5-Bromopicolinaldehyde (3.53 g, 18.89 mmol) was reacted with TosMIC (4.26 g, 21.82 mmol) and K2CO3 (3.15 g, 22.78 mmol) as per General Procedure 14 in MeOH (40 mL) to provide 5-(5-bromopyridin-2-yl)oxazole (3.84 g, 90%) as a pale yellow solid.
References:
WO2021/12018,2021,A1 Location in patent:Page/Page column 63; 185
31181-90-5
330 suppliers
$5.00/250mg
36635-61-7
498 suppliers
$5.00/5g
380380-74-5
13 suppliers
$124.00/500mg