5-pyridin-4-yl-1,3,4-oxadiazol-2-amine synthesis
- Product Name:5-pyridin-4-yl-1,3,4-oxadiazol-2-amine
- CAS Number:704-56-3
- Molecular formula:C7H6N4O
- Molecular Weight:162.15
Yield:704-56-3 77%
Reaction Conditions:
Stage #1: isoniazid;bromocyane in methanol at 55 - 56; for 2 h;
Stage #2: with sodium hydrogencarbonate in methanol;Cooling;
References:
Patel, Manishkumar B.;Modi, Nishith R.;Raval, Jignesh P.;Menon, Shobhana K. [Organic and Biomolecular Chemistry,2012,vol. 10,# 9,p. 1785 - 1794] Location in patent:experimental part
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