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393861-00-2

(5-(THIOPHEN-2-YL)PYRIDIN-3-YL)METHANOL synthesis

2synthesis methods
6165-68-0 Synthesis
2-Thiopheneboronic acid

6165-68-0
397 suppliers
$14.00/5g

37669-64-0 Synthesis
5-Bromo-3-pyridinemethanol

37669-64-0
216 suppliers
$12.00/1g

(5-(THIOPHEN-2-YL)PYRIDIN-3-YL)METHANOL

393861-00-2
23 suppliers
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Yield:393861-00-2 65%

Reaction Conditions:

with tetrakis(triphenylphosphine) palladium(0);sodium carbonate in methanol;toluene at 70; for 20 h;Suzuki coupling reaction;

References:

Shi;Wheelhouse;Sun;Hurley [Journal of Medicinal Chemistry,2001,vol. 44,# 26,p. 4509 - 4523]