6-chloro-7-nitroquinoline synthesis

2synthesis methods

635-22-3 Synthesis

56-81-5 Synthesis

Yield:226073-82-1 15 g

Reaction Conditions:

Stage #1: propane-1,2,3-triolwith sulfuric acid at 160; for 5 h;
Stage #2: 4-Chloro-3-nitroanilinewith sodium iodide at 110 - 150; for 18 h;

References:

WO2022/171110,2022,A1 Location in patent:Paragraph 068; 186; 187

635-22-3 Synthesis

56-81-5 Synthesis

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