6-Fluoro-2-phenylbenzoic acid synthesis

7synthesis methods

Product Name:6-Fluoro-2-phenylbenzoic acid
CAS Number:1841-56-1
Molecular formula:C13H9FO2
Molecular Weight:216.21

108-86-1 Synthesis

108-86-1
496 suppliers
$10.00/5g

445-29-4 Synthesis

445-29-4
413 suppliers
$5.00/10g

2367-22-8
32 suppliers
$45.00/100mg

1841-56-1
18 suppliers
$155.00/500mg

Yield:2367-22-8 71%

Reaction Conditions:

with copper(I) oxide;[ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂;triethylphosphonium tetrafluoroborate;potassium carbonate in 1-methyl-pyrrolidin-2-one at 190; for 18 h;Inert atmosphere;regioselective reaction;

References:

Biafora, Agostino;Krause, Thilo;Hackenberger, Dagmar;Belitz, Florian;Goo?en, Lukas J. [Angewandte Chemie - International Edition,2016,vol. 55,# 47,p. 14752 - 14755][Angew. Chem.,2016,vol. 128,p. 14972 - 14975,4] Location in patent:supporting information