Acetamide, 2-chloro-N-(4-fluorophenyl)-N-(1-methylethyl)- synthesis
- Product Name:Acetamide, 2-chloro-N-(4-fluorophenyl)-N-(1-methylethyl)-
- CAS Number:66602-64-0
- Molecular formula:C11H13ClFNO
- Molecular Weight:229.68
79-04-9
374 suppliers
$12.00/5g
70441-63-3
142 suppliers
$34.00/250mg
66602-64-0
8 suppliers
inquiry
Yield:66602-64-0 98%
Reaction Conditions:
with triethylamine in toluene at 20; for 5.5 h;Solvent;Temperature;
Steps:
1
To a 1000 mL three-necked flask equipped with a mechanical stirrer, thermometer and constant pressure dropping funnel were added 154.7 g of N-isopropyl-4-fluoroaniline, 102.2 of triethylamine and 400 mL of toluene, and 114 g of chloroacetyl chloride And the organic phase was washed with water, and the solvent was removed to obtain 228.7 g of the title compound. The organic layer was washed with water, and the solvent was evaporated under reduced pressure.2-chloro-N - (4-fluorophenyl) -N-isopropylacetamide,Purity 98.4%Yield 98%
References:
CN103664675,2016,B Location in patent:Paragraph 0014; 0016-0017
350-46-9
527 suppliers
$10.60/1gm:
66602-64-0
8 suppliers
inquiry