1,4-Piperidinedicarboxylic acid, 4-methyl-, 1-(1,1-dimethylethyl) 4-methyl ester synthesis
- Product Name:1,4-Piperidinedicarboxylic acid, 4-methyl-, 1-(1,1-dimethylethyl) 4-methyl ester
- CAS Number:724790-59-4
- Molecular formula:C13H23NO4
- Molecular Weight:257.33
124443-68-1
270 suppliers
$6.00/5g
74-88-4
339 suppliers
$15.00/10g
724790-59-4
65 suppliers
$45.00/250mg
Yield:724790-59-4 100%
Reaction Conditions:
Stage #1: 1-tert-Butyl 4-methyl piperidine-1,4-dicarboxylatewith potassium hexamethylsilazane in tetrahydrofuran;toluene at -78; for 1 h;Inert atmosphere;
Stage #2: methyl iodide in tetrahydrofuran;toluene at 20; for 20 h;Inert atmosphere;
References:
Atobe, Masakazu;Blakemore, David C.;Bond, Paul S.;Chan, Ngai S.;De Fusco, Claudia;Downes, Thomas D.;Firth, James D.;Hubbard, Roderick E.;Jones, S. Paul;Klein, Hanna F.;O'Brien, Peter;Roughley, Stephen D.;Vidler, Lewis R.;Waddelove, Laura;Whatton, Maria Ann;Wheldon, Mary C.;Woolford, Alison J.-A.;Wrigley, Gail L. [Chemistry - A European Journal,2020] Location in patent:supporting information
74-88-4
339 suppliers
$15.00/10g
724790-59-4
65 suppliers
$45.00/250mg
84358-13-4
385 suppliers
$5.00/5g
74-88-4
339 suppliers
$15.00/10g
724790-59-4
65 suppliers
$45.00/250mg
498-94-2
498 suppliers
$5.00/10g
724790-59-4
65 suppliers
$45.00/250mg
2971-79-1
285 suppliers
$10.00/10g
724790-59-4
65 suppliers
$45.00/250mg