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ChemicalBook CAS DataBase List N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-3'-O-tert-butyldimethylsilyl guanosine

N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-3'-O-tert-butyldimethylsilyl guanosine synthesis

4synthesis methods
18162-48-6 Synthesis
tert-Butyldimethylsilyl chloride

18162-48-6
656 suppliers
$9.00/5g

81279-39-2 Synthesis
N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu

81279-39-2
90 suppliers
$27.00/250mg

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Yield:81256-89-5 34% ,81279-39-2 63%

Reaction Conditions:

in dichloromethane at 20;

References:

Wexselblatt, Ezequiel;Katzhendler, Jehoshua;Saleem-Batcha, Raspudin;Hansen, Guido;Hilgenfeld, Rolf;Glaser, Gad;Vidavski, Roee R. [Bioorganic and Medicinal Chemistry,2010,vol. 18,# 12,p. 4485 - 4497] Location in patent:scheme or table

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