tert-Butyldimethylsilyl chloride
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tert-Butyldimethylsilyl chloride Properties
- Melting point:
- 86-89 °C
- Boiling point:
- 125 °C(lit.)
- Density
- 0.87 g/mL at 20 °C(lit.)
- refractive index
- n
20/D 1.46
- Flash point:
- 73 °F
- storage temp.
- Store at 5°C
- form
- Liquid
- color
- Clear colorless
- Specific Gravity
- 1.225
- Water Solubility
- Soluble in chloroform and ethyl acetate. Insoluble in water.
- Hydrolytic Sensitivity
- 7: reacts slowly with moisture/water
- Hydrolytic Sensitivity
- 8: reacts rapidly with moisture, water, protic solvents
- Sensitive
- Moisture Sensitive
- BRN
- 505999
- InChIKey
- BCNZYOJHNLTNEZ-UHFFFAOYSA-N
- CAS DataBase Reference
- 18162-48-6(CAS DataBase Reference)
- EWG's Food Scores
- 1
- FDA UNII
- 550OPF5Z9F
- NCI Dictionary of Cancer Terms
- BDCS
- NIST Chemistry Reference
- Silane, chloro(1,1-dimethylethyl)dimethyl-(18162-48-6)
- EPA Substance Registry System
- Silane, chloro(1,1-dimethylethyl)dimethyl- (18162-48-6)
SAFETY
- Risk and Safety Statements
| Symbol(GHS) |     GHS07,GHS08,GHS02,GHS05 |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||||
| Hazard statements | H225-H304-H314-H336-H361d-H373-H302-H335-H351-H226-H228-H318-H361 | |||||||||||
| Precautionary statements | P309-P240-P241-P264-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P405-P501-P210-P261-P280-P301+P310-P305+P351+P338-P310-P260-P370+P378-P403+P235 | |||||||||||
| Hazard Codes | C,F,T,Xn | |||||||||||
| Risk Statements | 22-35-40-34-10-19-11-67-65-63-48/20-20/21/22-45-23/24/25-37-36/37/38 | |||||||||||
| Safety Statements | 26-36/37/39-46-62-45-25-16-28-27-33-29-53-36/37 | |||||||||||
| RIDADR | UN 2925 4.1/PG 2 |
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| WGK Germany | 2 |
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| RTECS | VV2000000 |
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| F | 10-21 | |||||||||||
| Hazard Note | Flammable/Corrosive/Moisture Sensitive | |||||||||||
| TSCA | Yes | |||||||||||
| HazardClass | 4.1 | |||||||||||
| PackingGroup | III | |||||||||||
| HS Code | 29310095 | |||||||||||
| NFPA 704 |
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tert-Butyldimethylsilyl chloride price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 06735 | tert-Butyldimethylsilyl chloride for GC derivatization, ≥99.0% (GC) | 18162-48-6 | 10g | $91.5 | 2020-08-18 | Buy |
| Sigma-Aldrich | 06735 | tert-Butyldimethylsilyl chloride for GC derivatization, ≥99.0% (GC) | 18162-48-6 | 10x1g | $106 | 2019-12-02 | Buy |
| TCI Chemical | B0995 | tert-Butyldimethylchlorosilane [tert-Butyldimethylsilylating Agent] >98.0%(GC) | 18162-48-6 | 5g | $24 | 2020-06-24 | Buy |
| TCI Chemical | B0995 | tert-Butyldimethylchlorosilane [tert-Butyldimethylsilylating Agent] >98.0%(GC) | 18162-48-6 | 25g | $79 | 2020-06-24 | Buy |
| Alfa Aesar | A13064 | tert-Butyldimethylchlorosilane 97% | 18162-48-6 | 25g | $86 | 2020-06-24 | Buy |
tert-Butyldimethylsilyl chloride Chemical Properties,Uses,Production
Introduction
Triethylchlorosilane is a clear, colourless to yellowish, pungent smelling, caustic and flammable liquid. It can be dissolved in non-protonating solvents without decomposition.It may be used as silylating agent for dervatization of primary and secondary alcohols etc.. Also it may be used to protect allylic esters as silylketene acetal which is ore stable but less volatile derivates than trimethylchlorosilane.
Chemical Properties
White solidUses
Used to protect alcohols during organic synthesis.Definition
ChEBI: A silyl chloride consisting of a central silicon atom covalently bound to one chloro, one tert-butyl and two methyl groups. tert-Butyldimethylsilyl chloride is a derivatisation agent used in gas chromatography/mass spectrometry ap lications.Hazard
Moderately toxic.Purification Methods
Fractionally distil it at atmospheric pressure. [Sommer & Tyler J Am Chem Soc 76 1030 1954, Corey & Venkateswarlu J Am Chem Soc 94 6190 1972, Beilstein 4 IV 4076.]tert-Butyldimethylsilyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
beta-Methyl vinyl phosphate (MAP)
(3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one
2-Chloro-4-nitrophenyl-alpha-L-fucopyranoside
Calcipotriene
Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester
2-CYANOPYRIDINE-4-CARBOXALDEHYDE
4-Mercaptophenylboronic acid
Montelukast
4-(HYDROXYMETHYL)PICOLINITRILE
5-(AMINOMETHYL)-1-METHYLPYRROLIDIN-2-ONE
Simvastatin
tert-Butyldimethylsilyl chloride Suppliers
Global( 528)Suppliers
| Supplier | Tel | Fax | Country | ProdList | Advantage | |
|---|---|---|---|---|---|---|
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 E-mail：sales03@shyrchem.com |
+86-21-34979012 | sales03@shyrchem.com | CHINA | 739 | 60 |
| Nanjing Sinoda Biological Technology Co., Ltd | 13401983379 0086-13401983379 |
0086-25-83151634 | sales@njmcn.cn | CHINA | 50 | 58 |
| Capot Chemical Co.,Ltd. | +86（0）13336195806 +86-571-85586718 |
+86-571-85864795 | sales@capotchem.com | China | 19929 | 60 |
| Henan DaKen Chemical CO.,LTD. | +86-371-55531817 |
info@dakenchem.com | CHINA | 21804 | 58 | |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
010-60279497 | sales01@cooperate-pharm.com | CHINA | 1817 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | 0371-55170693 |
0371-55170693 | info@tianfuchem.com | CHINA | 22623 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 |
+86-021-57951555 | jack.li@time-chemicals.com | CHINA | 1365 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 0086 158 5814 5714 (Mobile |
+86-571-56059825 | fandachem@gmail.com | CHINA | 3286 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +86 21 5161 9050/ 5187 7795 |
+86 21 5161 9052/ 5187 7796 | ivan@atkchemical.com | CHINA | 24948 | 60 |
| Anhui Royal Chemical Co., Ltd. | +86-025-86655873 |
marketing@royal-chem.com | CHINA | 537 | 55 |
Related articles
- What is tert-Butyldimethylsilyl chloride?
- tert-Butyldimethylsilyl chloride may be used as silylating agent for dervatization of primary and secondary alcohols etc.. Als....
- Aug 13，2020
View Lastest Price from tert-Butyldimethylsilyl chloride manufacturers
| Image | Release date | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-10-15 |
tert-Butyldimethylsilyl chloride 18162-48-6 |
US $1.00 / KG | 1KG | 99% | 10T | Henan Xiangtong Chemical Co., Ltd. | |
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2020-11-09 |
Tert-Butyldimethylsilyl Chloride 18162-48-6 |
US $100.00 / Kg/Bag | 1Kg/Bag | 99 | 999 | Longyan Tianhua Biological Technology Co., Ltd | |
 |
2020-06-29 |
Tert-Butylchlorodimethylsilane;tert-Butyl(chloro)dimethylsilane;TBMS; CFS-486 18162-48-6 |
US $50.00 / KG | 1KG | min 99% | 10MT/month | Hubei Co-Formula Material Tech Co., Ltd. |
18162-48-6(tert-Butyldimethylsilyl chloride)Related Search:
2-Chloro-2-methylpropane Triethylsilane Fattyalkyl dimethyl amine Pivaloyl chloride Chloro(chloromethyl)dimethylsilane Ammonium chloride Potassium chloride Dimethyl phthalate Dimethyl sulfate DI-TERT-BUTYLDICHLOROSILANE Dimethyl sulfide Dimethyl sulfoxide ETHANE Calcium chloride Choline chloride CHLORIDE STANDARD DMC Dichlorodimethylsilane
- t-butylchlorodimethyl-silan
- SILANE TBM2
- SILANE, CHLORO(1,1-DIMETHYLETHYL)DIMETHYL-
- T-BUTYLDIMENHYLSILYL CHLORIDE
- t-butyl dimethyl chlorsilane
- T-BUTYLDIMETHYLCHLOROSILANE
- T-BUTYLDIMETHYLSILYL CHLORIDE
- TBDMSCI
- TBDMSCL
- TBDMCl
- TBDMCS
- TBUME2SI-CL
- TBSCL
- TERT-BUTYLDIMETHYLSILYL CHLORIDE
- TERT-BUTYLDIMETHYLCHLOROSILANE
- TERT-BUTYLCHLORODIMETHYLSILANE
- T-butyldimethylsilyl chloride*crystalline
- tert-Butyldimethylsilyl chloride~TBDMSCl~TBSCl
- tert-Butyl Dimethylchlorosilane (TBDMSCl)
- chloro-dimethyl-tert-butyl-silane
- Tert-butyldimethylsilyl chloride, TBSCI
- TERT-BUTYLDIMETHYLSILYL CHLORIDE, 50 WT. % SOLUTION IN TOLUENE
- TERT-BUTYLDIMETHYLCHLOROSILANE SOLUTION, ~50% IN TOLUENE
- TERT-BUTYLDIMETHYLCHLOROSILANE SOLUTION, 50% IN METHYL. CHL.
- tert-Butyldimethylchlorosilane [tert-Butyldimethylsilylating Agent]
- tert-Butyldimethylchlorosilane, 97+%
- tert-Butyldimethylchlorosilane, tert-Butyldimethylsilyl chloride, TBDMSCl solution
- tert-Butyldimethylchlorosilane, tert-Butyldimethylsilyl chloride, TBDMSCl
- tert-Butyl(chloro)dimethylsilane, tert-Butyldimethylchlorosilane, TBDMSCl
- t-BUTYLDIMETHYLCHLOROSILANE, 2.85M in toluene, 49-50% solution
- t-BUTYLDIMETHYLCHLOROSILANE, 3M in tetrahydrofuran
- tert-Butyldimethylchlorosilane, tert-Butyldimethylsilyl chloride, Silane TBM2-Tol Sol., TBDMSCl solution
- tert-Butyldimethylchlorosilane, tert-Butyldimethylsilyl chloride, Silane TBM2, TBDMSCl
- t-Butyldimethylchlorosilane, min. 97%
- tert-Butylchlorodimethylsilane1.0M solution in dichloromethaneAcroSeal§3
- tert-Butylchlorodimethylsilane,98%
- tert-Butyldimethylsilyl
- t-Butyldimethylchlorosilane,min.97%
- TERT-BUTYLDIMETHYLCHLOROSILANE, 1.0 M IN METHYLENE CHLORIDE
- 2.85M IN TOLUENE (CA. 49.5%)
- TERT-BUTYLDIMETHYLCHLOROSILANE, 3M IN THF
- tert-Butylchlorodimethylsilane, 1.0M solution in dichloromethane
- tert-ButyldimethylchlorosilaneTBSCl
- tert-BUTYLDIMETHYLCHLOROSILANE 98%
- TERT-BUTYLDIMETHYLSILYL CHLORIDE (TBDMSCL)
- Tert-Butyldimethylchlorosilane50%W/WInToluene
- Tertbutyldimethylchlorosilane,ProtectiveReagent,
- Tbdmscl(Tert-ButyldimethylsilylChloride)
- Tert-ButyldimethylchlorosilaneTbms
- TBSCl (Tert-butyldimethylsilyl chloride)
- BDCS
- BDCS SILYLATION REAGENT
- CB2790
- chloro(1,1-dimethylethyl)dimethyl-silan
- chloro(1,1-dimethylethyl)dimethyl-Silane
- chloro-tert-butyldimethyl-silan
- Chloro-tert-butyldimethylsilane
- Dimethyl-tert-butylchlorosilane
