tert-Butyl N-(1,3-benzothiazol-2-ylMethyl)carbaMate synthesis
- Product Name:tert-Butyl N-(1,3-benzothiazol-2-ylMethyl)carbaMate
- CAS Number:864738-25-0
- Molecular formula:C13H16N2O2S
- Molecular Weight:264.34
4530-20-5
566 suppliers
$5.00/5G
137-07-5
318 suppliers
$10.00/5g
864738-25-0
10 suppliers
$320.00/5g
Yield:864738-25-0 78%
Reaction Conditions:
with iodine at 20; for 0.333333 h;
Steps:
Benzothiazoles 3a-3f and 4a-4f from N-protected amino acids (general procedure).
General procedure: The reaction between protected amino acid (500 mg, 2.7 mmol) and 2-aminothiophenol (0.67 mL, 5.3 mmol) in the presence of iodine (223 mg, 1.8 mmol) as a catalyst was carried out following the procedure described in [14]. The reaction was complete (TLC monitoring) in 20 min. The product was washed with aqueous Na2S2O3 to removeunreacted iodine and purified by recrystallization from a 70 : 30 ethanol-water mixture.
References:
Arfan, M.;Fatima, T.;Mannan, A.;Tahira, A. [Russian Journal of Organic Chemistry,2020,vol. 56,# 2,p. 292 - 297]
24424-99-5
863 suppliers
$13.50/25G
864738-25-0
10 suppliers
$320.00/5g
4530-20-5
566 suppliers
$5.00/5G
864738-25-0
10 suppliers
$320.00/5g