3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)benzonitrile synthesis
1synthesis methods
- Product Name:3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)benzonitrile
- CAS Number:923836-09-3
- Molecular formula:C16H14N2O2S
- Molecular Weight:298.36
Yield:923836-09-3 14%
Reaction Conditions:
with triethylamine in acetone at 0 - 20;
References:
Jamieson, Stephen M. F.;Brooke, Darby G.;Heinrich, Daniel;Atwell, Graham J.;Silva, Shevan;Hamilton, Emma J.;Turnbull, Andrew P.;Rigoreau, Laurent J. M.;Trivier, Elisabeth;Soudy, Christelle;Samlal, Sharon S.;Owen, Paul J.;Schroeder, Ewald;Raynham, Tony;Flanagan, Jack U.;Denny, William A. [Journal of Medicinal Chemistry,2012,vol. 55,# 17,p. 7746 - 7758] Location in patent:supporting information