ChemicalBook CAS DataBase List 6-CHLORO-1,2-DIHYDRO-2-OXOSPIRO[4H-3,1-BENZOXAZIN-4,4'-PIPERIDINE]

6-CHLORO-1,2-DIHYDRO-2-OXOSPIRO[4H-3,1-BENZOXAZIN-4,4'-PIPERIDINE] synthesis

1synthesis methods

Product Name:6-CHLORO-1,2-DIHYDRO-2-OXOSPIRO[4H-3,1-BENZOXAZIN-4,4'-PIPERIDINE]
CAS Number:92926-63-1
Molecular formula:C12H13ClN2O2
Molecular Weight:252.7

106-47-8 Synthesis

106-47-8
494 suppliers
$5.00/5G

6-CHLORO-1,2-DIHYDRO-2-OXOSPIRO[4H-3,1-BENZOXAZIN-4,4'-PIPERIDINE]

92926-63-1
46 suppliers
$51.00/100mg

Yield:-

Steps:

4

Amide coupling:-Amine: 6-chlorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one (described in WO0122919 A2, or prepared using the same procedure described in J. Med. Chem., 1983, 26(5), 657 starting with 4-chloro-aniline) Acid: 6-Chloro-1H-indole-3-carboxylic acid (described in example 2)

References:

US2007/155761,2007,A1 Location in patent:Page/Page column 16

6-CHLORO-1,2-DIHYDRO-2-OXOSPIRO[4H-3,1-BENZOXAZIN-4,4'-PIPERIDINE] Related Search:

6-CHLORO-1,2-DIHYDRO-2-OXOSPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDINE]-1'-CARBOXYLIC ACID 1,1-DIMETHYL ETHYL ESTER 4-(3-CHLORO-PHENYL)-PIPERIDIN-4-OL

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