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ChemicalBook CAS DataBase List 99FLUORENEDIPROPIONICACID

99FLUORENEDIPROPIONICACID synthesis

3synthesis methods
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Yield:4425-95-0 90.4%

Reaction Conditions:

Stage #1: 9H-fluorene;acrylic acidwith sodium methylate;N-benzyl-trimethylammonium hydroxide in 1,4-dioxane at 30; for 17 h;
Stage #2: with sodium hydroxide in 1,4-dioxane;water;
Stage #3: with hydrogenchloride in water;

References:

EP1215192,2002,A2 Location in patent:Example 5