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ChemicalBook CAS DataBase List AFLATOXIN B2
7220-81-7

AFLATOXIN B2 synthesis

4synthesis methods
A highly enantioselective [3+2]-cycloaddition reaction of 2,3-dihydrofuran with 1,4-benzoquinones using a chiral oxazaborolidinium triflimidate as catalyst has been developed by Corey and colleagues in 2005, which allows rapid access to a variety of chiral phenolic tricycles (enantiomeric excesses ranging from 91 to 98%). The utility of this new methodology is demonstrated by a short synthesis of the important pentacyclic natural product, aflatoxin B2.[1]
AFLATOXIN B2 synthesis

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