ChemicalBook >> CAS DataBase List >>AFLATOXIN B2

AFLATOXIN B2

CAS No.
7220-81-7
Chemical Name:
AFLATOXIN B2
Synonyms
AF B2;2,3,6aB1;8,9,9aB1;AFLATOXIN B2;Aflatoxine B2;AFLATOXIN B2(RG);Aflatoxin B2;AF B2;dihydroaflatoxinb1;Dihydroaflatoxin B1;Dihydroafflatoxin B1
CBNumber:
CB0236746
Molecular Formula:
C17H14O6
Molecular Weight:
314.29
MDL Number:
MFCD00078140
MOL File:
7220-81-7.mol
Last updated:2023-08-30 13:35:17

AFLATOXIN B2 Properties

Melting point 286-289 °C
alpha D -492° (c = 0.1 in CHCl3)
Boiling point 373.98°C (rough estimate)
Density 1.2564 (rough estimate)
refractive index 1.4800 (estimate)
Flash point 11 °C
storage temp. 2-8°C
solubility DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 12 mg/ml
Water Solubility 15mg/L(temperature not stated)
Merck 13,180
BRN 1355115
LogP 1.802 (est)
CAS DataBase Reference 7220-81-7
FDA UNII 7SKR7S646P

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H300+H310+H330-H340-H350
Precautionary statements  P201-P262-P280-P301+P310+P330-P302+P352+P310-P304+P340+P310
Hazard Codes  T+,T,F,Xn
Risk Statements  45-26/27/28-39/23/24/25-23/24/25-11-65-48/23/24/25-36/38-46-36-20/21/22
Safety Statements  53-36-45-36/37-26-62-28-16
RIDADR  UN 3462 6.1/PG 1
WGK Germany  3
RTECS  GY1722000
10
HazardClass  6.1(a)
PackingGroup  I
HS Code  29322090
Toxicity LD50 orally in day old duckling: 84.8 mg/50 gm body wt (Carnaghan)
NFPA 704
1
4 1

AFLATOXIN B2 price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CRM46324 Aflatoxin B2 solution certified reference material, 3?μg/mL in benzene:acetonitrile (98:2), ampule of 1?mL 7220-81-7 1mL $51.78 2024-03-01 Buy
Sigma-Aldrich 34034 Aflatoxin B2 solution 0.5?μg/mL in acetonitrile, analytical standard 7220-81-7 2ml $339 2024-03-01 Buy
Sigma-Aldrich 32755 Aflatoxin B2 reference material 7220-81-7 5mg $2070 2024-03-01 Buy
Cayman Chemical 11294 Aflatoxin B2 ≥98% 7220-81-7 1mg $72 2024-03-01 Buy
Cayman Chemical 11294 Aflatoxin B2 ≥98% 7220-81-7 5mg $283 2024-03-01 Buy
Product number Packaging Price Buy
CRM46324 1mL $51.78 Buy
34034 2ml $339 Buy
32755 5mg $2070 Buy
11294 1mg $72 Buy
11294 5mg $283 Buy

AFLATOXIN B2 Chemical Properties,Uses,Production

Chemical Properties

The aflatoxins are a group of molds produced by the fungus Aspergillus flavus. They are natural contaminants of fruits, vegetables, and grains. They are also described as a series of condensed ring heterocyclic compounds. They form colorless to pale yellow crystals. Practically insoluble in water.

Chemical Properties

off-white powder

Uses

Aflatoxin B2 is the minor analogue of the blue fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins", requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts, particularly in grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed.

Uses

Aflatoxins are naturally occuring mycotoxins produced by various species of the mold Aspergillus, which can be found in legumes, corn, soybeans, rice, milk, and cheese. They are highly carcinogenic substances that are metabolized by the liver to a reactive epoxide intermediate, which produces adducts that modify DNA. Aflatoxin B1 induces transversion of G to T at codon 249 of the p53 tumor suppressor gene. This transversion is common in hepatocellular carcinoma patients living in regions with high levels of aflatoxin contamination. Aflatoxin B2 is the dihydro derivative of aflatoxin B1, a naturally occuring mycotoxin and food contaminant that is a likely pathogen that causes hepatocellular carcinoma.[Cayman Chemical]

Uses

Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects.

Definition

ChEBI: An aflatoxin having a hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.

General Description

Aflatoxin B2 is one of the fungal metabolic products produced in food and feed, contaminated by?Aspergillus?species.

Safety Profile

Confirmed human carcinogen with experimental tumorigenic data. Poison by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and fumes. See also various aflatoxins.

Potential Exposure

Aflatoxins are a group of toxic metabolites produced by certain types of fungi. Aflatoxins are not commercially manufactured; they are naturally occurring contaminants that are formed by fungi on food during conditions of high temperatures and high humidity. Most human exposure to aflatoxins occurs through ingestion of contaminated food. The estimated amount of aflatoxins that Americans consume daily is estimated to be 0.15 0.50 μg. Grains, peanuts, tree nuts, and cottonseed meal are among the more common foods on which these fungi grow. Meat, eggs, milk, and other edible products from animals that consume aflatoxincontaminated feed may also contain aflatoxins. Aflatoxins can also be breathed in

Shipping

UN3172 Toxins, extracted from living sources, solid or liquid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Use of oxidizing agents, such as hydrogen peroxide or 5% sodium hypochlorite bleach. Acids and bases may also be used.

2880-58-2
7220-81-7
Synthesis of AFLATOXIN B2 from METHOXYBENZOQUINONE

AFLATOXIN B2 Preparation Products And Raw materials

Global( 126)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10326 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
86 18062405514 18062405514 ada@ipurechemical.com CHINA 3465 58
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9702 58
Shijiazhuang Tongyang Import and Export Co., LTD
18031361688; admin@sjztongyang.com China 987 58
Guangzhou TongYi biochemistry technology Co.,LTD
+8613073028829 mack@tongyon.com China 2996 58

View Lastest Price from AFLATOXIN B2 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AFLATOXIN B2 pictures 2023-08-30 AFLATOXIN B2
7220-81-7
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
AFLATOXIN B2 pictures 2021-08-07 AFLATOXIN B2
7220-81-7
US $1.00 / KG 1KG 99% 10 mt Hebei Guanlang Biotechnology Co., Ltd.
  • AFLATOXIN B2 pictures
  • AFLATOXIN B2
    7220-81-7
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
  • AFLATOXIN B2 pictures
  • AFLATOXIN B2
    7220-81-7
  • US $1.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.
AFLATOXIN B2 (6ar-cis)-hexahydro-4-methoxy ,9,9a-alpha-hexahydro-4-methoxy- 2,3,6aalpha,8,9,9aalpha-hexahydro-4-methoxycyclopenta(c)furo(3’,2’:4,5)furo(2, Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6aalpha,8,9,9aalpha-hexahydro-4-methoxy- Dihydroafflatoxin B1 Dihydroaflatoxin B1 dihydroaflatoxinb1 2,3,6aalpha,8,9,9aalpha-hexahydro-4-methoxycyclopenta[c]furo[2',3':4,5]furo[2,3-h]chromene-1,11-dione AF B2 Aflatoxin B2;AF B2 aflatoxin b2 solution aflatoxin b2solution AFLATOXIN B2(RG) dihydroaflatoxine b1 AFLATOXIN B2 FROM ASPERGILLUS FLAVUS AFLATOXIN B2-LOESUNG 5 NG/MYL IN METHANO AFLATOXIN B(2) FROM ASPERGILLUS FLAVUS, VIAL WITH 10 MG AflatoxinB2,crystalline 3-h)(1)benzopyran-1,11-dione 4-Methoxy-2,3,6a,8,9,9a-hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-H]chromene-1,11-dione 9aalpha-hexahydro-4-methoxy- cyclopenta(c)furo(3’,2’:4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6a-alpha,8 cyclopenta(c)furo(3’,2’:4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6aalpha,8, Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,8,9,9a-hexahydro-4-methoxy-, (6aR-cis)- (6aR)-2,3,6aα,8,9,9aα-Hexahydro-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione (6aR,9aS)-2,3,6a,8,9,9a-Hexahydro-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione Aflatoxine B2 Aflatoxin B2 Dihydroaflatoxine B1 Aflatoxin B2 Solution in Acetonitrile, 100μg/mL Aflatoxin B2 0.5ug/ml in ACN Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,8,9,9a-hexahydro-4-methoxy-, (6aR,9aS)- AflatoxinB2Solution,3mg/L Aflatoxin B2, 98%, from Aspergillus flavus (6aR,9aS)-4-methoxy-2,3,9,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11(6aH,8H)-dione 2,3,6aB1 8,9,9aB1 -hexahydro-4-methoxycyclopenta[c]furo[2',3':4,5]furo[2,3-h]chromene-1,11-dione 7220-81-7 C17H14O6 BioChemical Cancer Research Carcinogens Other antibiotic Chiral Reagents Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Biotoxins Mycotoxins Single component solutions Cancer Research CarcinogensCell Signaling and Neuroscience Mold Toxins and Venoms CRM&Matrix RMApplication CRMs