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ChemicalBook CAS DataBase List Amlexanox

Amlexanox synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 95 percent / piperidine / ethanol / 5 h / Heating
2: 88 percent / 50percent aq. H2SO4, AcOH / 3 h / 130 °C

References:

Nohara;Ishiguro;Ukawa;Sugihara;Maki;Sanno [Journal of Medicinal Chemistry,1985,vol. 28,# 5,p. 559 - 586]

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