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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List Tris(hydroxymethyl)aminomethane

Tris(hydroxymethyl)aminomethane synthesis

3synthesis methods
Tris is prepared industrially by the exhaustive condensation of nitromethane with formaldehyde under basic conditions (i.e. repeated Henry reactions) to produce the intermediate (HOCH2)3CNO2, which is subsequently hydrogenated to give the final product.
79-06-1 Synthesis
Acrylamide

79-06-1
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Tris(hydroxymethyl)aminomethane

77-86-1
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-

Yield:-

Steps:

Materials

40% Acrylamide:bisacrylamide solution (19:1)
Tris base
Boric acid (H3BO3)
Urea

References:

Walker, Sarah E.;Lorsch, Jon [Methods in Enzymology,2013,vol. 529,p. 171 - 184]

126-11-4 Synthesis
Tris(hydroxymethyl)nitromethane

126-11-4
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Tris(hydroxymethyl)aminomethane

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References
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, conjugate acid (1:1)

19320-52-6
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Tris(hydroxymethyl)aminomethane

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References

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