ChemicalBook CAS DataBase List Benzyltriethylammonium bromide

Benzyltriethylammonium bromide synthesis

4synthesis methods

Product Name:Benzyltriethylammonium bromide
CAS Number:5197-95-5
Molecular formula:C13H22BrN
Molecular Weight:272.22

100-39-0

121-44-8

5197-95-5

GENERAL METHOD: Benzyl halide (1 eq.) was dissolved in THF (50 mL/g benzyl halide) with reference to the method described in Ref. 4, to which 1.5 eq. of triethylamine (33 wt% ethanol solution) was subsequently added. The reaction mixture was stirred at room temperature for 24 h. The product precipitated as a white solid during the reaction. The resulting suspension was cooled to 0 °C, filtered, and the filter cake was washed with ice-cold ether and finally dried under vacuum to afford the target product benzyltriethylammonium bromide in a yield consistent with literature reports.

100-39-0
434 suppliers
$10.00/10 g

121-44-8 Synthesis

121-44-8
900 suppliers
$9.00/5g

5197-95-5
350 suppliers
$10.00/5g

Yield:5197-95-5 98%

Reaction Conditions:

in tetrahydrofuran;ethanol at 25; for 24 h;Inert atmosphere;

Steps:

General Procedure
General procedure: In analogy to literature⁴, to a solution of benzyl halide 9 (1 equiv.) in THF (50 ml/g benzyl halide) were added 1.5 equiv. of trimethylamine 10 (33 wt% in EtOH).The resulting solution was stirred at RT for 24 hours, during which the product precipitated asa white solid. The resulting suspension was cooled to 0 °C, filtrated, washed with ice-cold Et2O and dried in vacuo to yield benzyl ammonium salts 6 in the reported yields.

References:

Roiser, Lukas;Robiette, Raphaël;Waser, Mario [Synlett,2016,vol. 27,# 13,art. no. ST-2016-B0225-L,p. 1963 - 1968] Location in patent:supporting information

FullText

74-96-4 Synthesis