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ChemicalBook CAS DataBase List CEP 33779

CEP 33779 synthesis

3synthesis methods
747413-17-8 Synthesis
1-(3-broMophenyl)-4-Methylpiperazine

747413-17-8
24 suppliers
$171.19/100mg

[1,2,4]Triazolo[1,5-a]pyridin-2-amine, 8-[4-(methylsulfonyl)phenyl]-

1257704-13-4
3 suppliers
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Yield:1257704-57-6 36%

Reaction Conditions:

with dicyclohexyl-({2-[2-(dicyclohexylphosphanyl)phenyl]-phenyl})-phosphane;palladium diacetate;caesium carbonate in 1,4-dioxane at 100; for 72 h;Inert atmosphere;Buchwald-Hartwig coupling;

References:

Dugan, Benjamin J.;Gingrich, Diane E.;Mesaros, Eugen F.;Milkiewicz, Karen L.;Curry, Matthew A.;Zulli, Allison L.;Dobrzanski, Pawel;Serdikoff, Cynthia;Jan, Mahfuza;Angeles, Thelma S.;Albom, Mark S.;Mason, Jennifer L.;Aimone, Lisa D.;Meyer, Sheryl L.;Huang, Zeqi;Wells-Knecht, Kevin J.;Ator, Mark A.;Ruggeri, Bruce A.;Dorsey, Bruce D. [Journal of Medicinal Chemistry,2012,vol. 55,# 11,p. 5243 - 5254] Location in patent:experimental part

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