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Ethyl-2,2-difluoro-2-(4-methylphenyl)acetate synthesis

6synthesis methods
-

Yield:131323-06-3 85%

Reaction Conditions:

with (dimethylamido)sulfur trifluoride at 0 - 20;

References:

Tilley, Jefferson W.;Danho, Waleed;Lovey, Kathleen;Wagner, Rolf;Swistok, Joseph;et al. [Journal of Medicinal Chemistry,1991,vol. 34,# 3,p. 1125 - 1136]