ChemicalBook CAS DataBase List ETHYL (4-IODOBENZOYL)ACETATE

ETHYL (4-IODOBENZOYL)ACETATE synthesis

4synthesis methods

Product Name:ETHYL (4-IODOBENZOYL)ACETATE
CAS Number:63131-30-6
Molecular formula:C11H11IO3
Molecular Weight:318.11

141-78-6 Synthesis

141-78-6
590 suppliers
$22.37/250ml

1711-02-0 Synthesis

1711-02-0
162 suppliers
$10.00/1g

63131-30-6
56 suppliers
$75.90/0.5g

Yield:63131-30-6 81%

Reaction Conditions:

Stage #1: ethyl acetatewith lithium diisopropyl amide in tetrahydrofuran at -78;
Stage #2: 4-iodobenzoic acid chloride in tetrahydrofuran at -78 - 20;

References:

Hylsová, Michaela;Carbain, Benoit;Fanfrlík, Jind?ich;Musilová, Lenka;Haldar, Susanta;K?prülüo?lu, Cemal;Ajani, Haresh;Brahmkshatriya, Pathik S.;Jorda, Radek;Kry?tof, Vladimír;Hobza, Pavel;Echalier, Aude;Paruch, Kamil;Lep?ík, Martin [European Journal of Medicinal Chemistry,2017,vol. 126,p. 1118 - 1128]

13329-40-3 Synthesis