indole-3-aldehyde oxime synthesis
- Product Name:indole-3-aldehyde oxime
- CAS Number:2592-05-4
- Molecular formula:C9H8N2O
- Molecular Weight:160.17
487-89-8
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2592-05-4
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$31.69/250mg
Yield:2592-05-4 83%
Reaction Conditions:
with acetylhydroxamic acid;boron trifluoride diethyl etherate in methanol; for 0.1 h;Microwave irradiation;Sealed tube;
Steps:
Procedure under microwave heating
General procedure: Benzaldehyde 1a (1.0 g, 9.4 mmol), acetohydroxamic acid (1.1 g, 14.1 mmol), methanol (1 ml) were taken in a 10 ml pressure tube and to this, BF3.OEt2 (135 μl, 0.94 mmol) was added and the mixture was subjected to microwave heating (CEM discover, 360 W, 70 °C, 25 psi) for 6 min. The crude product obtained was purified as mentioned above to afford benzaldoxime 2a (1.1 g, 95%), which gave spectral data same as above.
References:
Sridhar, Madabhushi;Narsaiah, Chinthala;Raveendra, Jillella;Kondal Reddy, Godala;Kishore Kumar Reddy, Mallu;China Ramanaiah, Beeram [Tetrahedron Letters,2011,vol. 52,# 36,p. 4701 - 4704] Location in patent:experimental part
120-72-9
614 suppliers
$6.00/25g
2592-05-4
56 suppliers
$31.69/250mg