m-Toluidine synthesis
- Product Name:m-Toluidine
- CAS Number:108-44-1
- Molecular formula:C7H9N
- Molecular Weight:107.15
625-95-6
252 suppliers
$14.00/25g
108-44-1
366 suppliers
$9.00/1g
Yield:108-44-1 90%
Reaction Conditions:
with ammonium hydroxide;caesium carbonate in acetonitrile for 7 h;Reflux;Green chemistry;
Steps:
3. 2. General Procedure
General procedure: A mixture of the aryl halide (1 mmol), NH4OH (2 mmol), Cs2CO3 (1 mmol) and P4PVy-CuI (0.1 g) in CH3CN (10 mL) was stirred at reflux temperature. After reaction completion (moitored by TLC), the catalyst was recovered by filtration and solvent was evaporated. The residue was poured into a saturated NaCl solution, extracted with ethyl acetate and dried over anhydrous MgSO4. Evaporation of the solvent was followed by column chromatography on silica gel afforded the pure products.
References:
Albadi, Jalal;Shiran, Jafar Abbasi;Mansournezhad, Azam [Acta Chimica Slovenica,2014,vol. 61,# 4,p. 900 - 903]
99-61-6
625 suppliers
$5.00/10g
108-44-1
366 suppliers
$9.00/1g
591-17-3
247 suppliers
$10.00/10g
108-44-1
366 suppliers
$9.00/1g
99-08-1
203 suppliers
$5.00/5 g
108-44-1
366 suppliers
$9.00/1g
588-04-5
54 suppliers
$74.00/1g
108-44-1
366 suppliers
$9.00/1g