ChemicalBook CAS DataBase List MBAA

MBAA synthesis

5synthesis methods

Product Name:MBAA
CAS Number:7330-46-3
Molecular formula:C15H14N2O4
Molecular Weight:286.28

50-00-0 Synthesis

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Yield:-

Reaction Conditions:

with hydrogenchloride in water at 70; for 40 h;Product distribution / selectivity;

Steps:

Anthranilic acid (10 g, 73.2 mmol) was dissolved in water (400 ml). Formaldehyde 37% solution in water (3 g, 36.8 mmol) and HCl 37% solution in water (7.2 g, 73.2 mmol) were added. The solution was stirred at 70° C. for 40 hours. The dispersion was filtered and the filtrate was evaporated under reduced pressure. The crude product was used in the next step without further purification (7.8 g, 58%).MS: [M-2H]^-=284

References:

US2010/280268,2010,A1 Location in patent:Page/Page column 32