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ChemicalBook CAS DataBase List ME0328
1445251-22-8

ME0328 synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: toluene
2: potassium carbonate; urea hydrogen peroxide adduct / acetone; water
3: 1-hydroxy-7-aza-benzotriazole; diisopropyl-carbodiimide / N,N-dimethyl-formamide / 19 h / 20 °C

References:

Lindgren, Anders E.G.;Karlberg, Tobias;Ekblad, Torun;Spjut, Sara;Thorsell, Ann-Gerd;Andersson, C. David;Nhan, Ton Tong;Hellsten, Victor;Weigelt, Johan;Linusson, Anna;Schueler, Herwig;Elofsson, Mikael [Journal of Medicinal Chemistry,2013,vol. 56,# 23,p. 9556 - 9568]

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